Search on: PLASMINOGEN INACTIVATORS 
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Descriptor English:   Plasminogen Inactivators 
Descriptor Spanish:   Inactivadores Plasminogénicos 
Descriptor Portuguese:   Inativadores de Plasminogênio 
Synonyms English:   Plasminogen Activator Inhibitors  
Tree Number:   D12.776.872.695
Definition English:   Important modulators of the activity of plasminogen activators. Four inhibitors, all belonging to the serpin family of proteins, have been implicated in plasminogen activation inhibition. They are PAI-1; PAI-2; protease-nexin; and PROTEIN C INHIBITOR; (PAI-3). All inhibit both the tissue-type and urokinase-type plasminogen activators. 
Indexing Annotation English:   serpins; DF: PLASMINOGEN INACT
Pharmacological Action:   Serine Proteinase Inhibitors
 
History Note English:   90 
Allowable Qualifiers English:  
administration & dosage adverse effects
agonists analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications deficiency
diagnostic use economics
genetics history
immunology isolation & purification
metabolism pharmacology
physiology pharmacokinetics
poisoning radiation effects
supply & distribution secretion
standards toxicity
therapeutic use urine
Record Number:   24836 
Unique Identifier:   D015849 

Occurrence in VHL: 		 

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